Neonatal Disseminated Herpes Simplex Virus Infection Triggering Extreme Hyperferritinemia Concerning for Hemophagocytic Lymphohistiocytosis
نویسندگان
چکیده
منابع مشابه
Neonatal herpes simplex virus infection
Neonatal herpes simplex virus (HSV) infections may be caused by either herpes simplex virus type-1 (HSV-1) or herpes simplex virus type-2 (HSV-2). In the United States, HSV-2 is responsible for 75% of genital and neonatal infections, while HSV-1 causes the rest. HSV-1 more commonly affects the oropharynx, the eyes and the central nervous system.1,2 It is estimated that 20 to 30% of sexually act...
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Fingolimod is an oral, disease-modifying therapy used to treat multiple sclerosis (MS). However, severe viral infections, including disseminated varicella-zoster virus infection, herpes simplex encephalitis, varicella-zoster virus encephalitis and vasculopathy, or progressive multifocal leukoencephalopathy, have been reported during fingolimod therapy. Hemophagocytic lymphohistiocytosis (HLH), ...
متن کاملRelapse of neonatal herpes simplex virus infection.
BACKGROUND Neonatal herpes simplex virus (HSV) infection is a severe disease with high mortality and morbidity. Recurrence of skin vesicles is common. OBJECTIVE To determine the features of relapse and identify the factors related to relapse. DESIGN Thirty two surviving patients with neonatal herpes virus infections were enrolled. All patients received acyclovir treatment. Clinical and viro...
متن کاملNeonatal herpes simplex infection.
Tremendous advances have occurred over the past 30 years in the diagnosis and management of neonatal herpes simplex virus (HSV) disease. Mortality in patients with disseminated disease has decreased from 85 to 29%, and that in patients with central nervous system (CNS) disease has decreased from 50 to 4%. Morbidity has been improved more modestly: the proportion of patients with disseminated di...
متن کاملHemophagocytic lymphohistiocytosis associated with SFTS virus infection
BACKGROUND Severe fever with thrombocytopenia syndrome (SFTS) is a new emerging zoonosis. Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome caused by hyperinflammation. Here, we report the case of SFTS-associated HLH. CASE SUMMARY A 62-year-old man was admitted to local hospital with 8 days of fever and chill. He had leukopenia, thrombocytopenia, and developed seizure. A...
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ژورنال
عنوان ژورنال: Journal of Investigative Medicine High Impact Case Reports
سال: 2019
ISSN: 2324-7096,2324-7096
DOI: 10.1177/2324709619862840